Growth hormone is significantly involved in cellular proliferation and efficiency as well as the production of IGF-1, which is also involved in cellular growth, repair and cell survival. After the third decade of life, there is a progressive decline of GH secretion by approximately 15% for every decade of adult life. Integrated measurements of daily GH secretion demonstrate that secretion peaks at puberty at about 150 µg/kg/day, then decreases to approximately 25 µg/kg/day by age 55. We can postulate (based off of an abundance of research that growth hormone is involved in a multitude of physiologic processes) that restoring growth hormone levels in aging adults can improve overall cellular efficiency, decrease cellular senescence and have a positive downstream effect on all of the organ systems and functions in the human body.